Tuesday, October 27, 2026 ยท WOMEN'S EDITION
LongevityMorning
What's new in feeling better and living longer. 5-minute read.
Good morning. Today: what nearly 6 million 23andMe health reports turned up, a genetic twist on aspirin and dementia, and a huge study on tea and blood vessels.
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01 ยท AT-HOME TESTING
About 1 in 10 23andMe users got a medically actionable result
Of nearly 6 million U.S. research participants who got 23andMe's FDA-authorized health risk reports from 2017 to 2025, more than 635,000 (10.6%) had at least one result tied to a condition with screening or prevention options.
Why it matters: At-home DNA kits can flag inherited risks, including BRCA variants linked to hereditary cancer, that people may not know they carry.
The details: The reports cover 91 variants in 20 genes. Results included nearly 11,800 in BRCA1, BRCA2 and MUTYH (hereditary cancer), more than 21,000 in genes tied to cardiovascular disease and more than 430,000 tied to inherited clotting disorders. Opt-in for hereditary cancer reports was at least 87.8% across every demographic group analyzed.
Yes, but: These are early findings presented at the American Society of Human Genetics meeting and shared in a press release from 23andMe's nonprofit research institute; it isn't clear they've been peer reviewed.
02 ยท BRAIN HEALTH
Low-dose aspirin was tied to less dementia in one genetic group
Among people with the highest genetic scores for platelet count, 1% of those taking low-dose aspirin developed dementia vs. 3.3% on placebo, in a new analysis of a major aspirin trial.
Why it matters: The trial, called ASPREE, previously found aspirin didn't prevent dementia overall; this hints that genetics might one day identify who could benefit.
The details: Monash University researchers studied more than 13,500 participants from the placebo-controlled trial in older adults, publishing in Alzheimer's & Dementia. The signal "wasn't linked to the established genetic risk factors" for dementia, lead author Dr. Peter Fransquet said.
Yes, but: In the same group, major bleeding was 4.4% on aspirin vs. 2.1% on placebo. It's an exploratory subgroup finding that needs its own trial, and Fransquet said people "shouldn't start taking aspirin to prevent dementia on the basis of this study without consulting with their doctor."
03 ยท NUTRITION ยท HEART HEALTH
Regular tea drinkers had less vascular disease in a 486,000-person study
Adults who drank tea at least three days a week had an 11% lower relative risk of vascular disease over about nine years, with the lowest risk around 6 to 8 cups a day.
Why it matters: Vascular disease covers heart disease, stroke and peripheral artery disease, and tea is one of the world's most common drinks.
The details: The study, in the Journal of Internal Medicine, followed 485,934 people in the China Kadoorie Biobank. Black tea showed the biggest reduction, and green tea was also tied to lower risk. Tea that felt "burning hot" was linked to a 16% higher risk than not drinking tea.
Yes, but: It's observational, intake was measured once and cup sizes weren't standardized. A British Heart Foundation dietitian said "we shouldn't treat that as a recommended amount," and another expert called the black-tea and hot-tea findings exploratory.
Source: Medical News Today
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Quick Hits
Alcohol's lifetime math. A new analysis in the Journal of Studies on Alcohol and Drugs estimated that Americans averaging 14 drinks a week face about a 1 in 25 lifetime risk of alcohol-related death, and found no significant overall protective effect at any level. ScienceDaily
Endometriosis and migraine. A Mayo Clinic review of 35 studies covering more than 13 million females found those with endometriosis had 2.3 times the odds of also having migraine; it was presented at the American Neurological Association meeting and isn't peer reviewed yet. Healthline
Sleep gummies, in mice. Mice given cannabinol (CBN), a cannabinoid sold in sleep gummies, twice a day for three days became less responsive to it and showed withdrawal signs, a UConn study found; it wasn't tested in people. ScienceDaily
Drinks and mouth bacteria. In a not-yet-peer-reviewed study of 5,598 U.S. adults, higher alcohol intake was linked to more of some bacteria previously tied to poor oral health, with liquor showing the biggest jump in bacterial variety; it can't show cause and effect. News-Medical
See you tomorrow morning.
LongevityMorning is for informational purposes only and isn't medical advice.
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