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Wednesday, October 28, 2026 ยท MEN'S EDITION
LongevityMorning
What's new in feeling better and living longer. 5-minute read.
Good morning. Today: a 15-year look at testosterone and health, a trial pairing an eating window with exercise, and the first national count of "food noise."
01 ยท HORMONES
Men with lower testosterone at 31 reported good health at 46
In a Finnish study following 2,691 men for 15 years, those with the lowest testosterone at age 31 generally reported good health and quality of life at 46.
Why it matters: Testosterone testing and treatment are booming, and "low T" is often framed as a health problem on its own.
The details: Men in the Northern Finland Birth Cohort 1966 had testosterone measured once at 31. The lowest quarter (below 17.2 nmol/L) was still within the usual clinical range. Self-rated health didn't differ significantly across groups, and higher odds of metabolic and digestive disease in lower-testosterone men disappeared after accounting for waist size.
Yes, but: The lowest group had higher depression scores. It's observational, testosterone was measured once, and 30% to 39% of men lacked some outcome data. The authors cautioned against unnecessary testosterone therapy, though the study didn't test treatment. Published in Endocrine Connections; coverage didn't report funding. Talk to your doctor.
02 ยท WEIGHT LOSS ยท TRAINING
An eating window plus exercise cut more body fat, but the edge faded in a year
In a 12-week Spanish trial of 187 adults with obesity, combining an eight-hour eating window with supervised exercise led to more body fat loss than standard care or exercise alone.
Why it matters: Time-restricted eating and pairing it with strength and interval training are both popular, and this trial tested them head to head.
The details: Participants were randomized to standard care, time-restricted eating, supervised exercise (strength plus high-intensity aerobic training) or both. Both eating-window groups lost about 2.2 kg (roughly 5 lb) more than standard care. Among those with fatty liver at the start, about 30% of the combined group no longer met the criteria vs. 6.5% with standard care.
Yes, but: Liver fat, the main outcome, fell in all four groups with no significant differences between them. At one-year follow-up, the weight and body composition differences were gone. Published in Nature Communications (the TEMPUS trial); funded by Spanish government and EU grants.
03 ยท APPETITE ยท WEIGHT
Up to 1 in 10 U.S. adults reported "food noise" in a first national estimate
A survey of 3,646 U.S. adults found that 4% to 9.5% met criteria for "food noise," persistent and unwanted thoughts about food, depending on the definition used.
Why it matters: The phrase is everywhere in weight-loss conversations, but there's been little data on how common it actually is.
The details: Drexel University and UC Irvine researchers used a five-item questionnaire in a nationally representative panel, excluding current GLP-1 users. Among adults with obesity, 6% to 13.7% met the criteria. Scores were higher in people with higher BMI, in adults under 60 and in women.
Yes, but: "A greater proportion of adults with obesity met the criteria, but most did not," the authors wrote. No clinically validated threshold exists, the survey is a one-time snapshot, and the study is a preprint under review at the International Journal of Obesity, not yet peer reviewed.
WATCH, LISTEN, SCROLL ยท THE BEST OF THE WEEK
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PODCAST
The Model Health Show: The Hard Truth About Sexual Fitness | Dr. Rena Malik
Out Oct. 25, urologist Dr. Rena Malik on how diet, exercise, sleep and stress affect sexual health, including testosterone and pelvic floor strength.
Quick Hits
Where GLP-1s come from. In a not-yet-peer-reviewed survey of 9,150 U.S. adults, GLP-1 use rose from 8.2% to 12% between March 2024 and October 2025, and about a third of users got the drugs through online providers, med spas, compounding or foreign pharmacies, or without a prescription. News-Medical
Activity and depression genes. In NIH All of Us data combining genetics and Fitbit records, genetic risk was less strongly linked to depression severity among adults who took more steps or logged more moderate-to-vigorous activity, per a study in Nature Mental Health. News-Medical
Mediterranean diet microproteins. In a small observational USC study, older adults who followed the Mediterranean diet more closely had higher blood levels of humanin and SHMOOSE, mitochondrial microproteins being studied for heart and brain health; it can't show cause and effect. ScienceDaily
See you tomorrow morning.
LongevityMorning is for informational purposes only and isn't medical advice.